7-METHOXYCARBONYL-1H-INDAZOLE-3-CARBOXYLIC ACID

7-METHOXYCARBONYL-1H-INDAZOLE-3-CARBOXYLIC ACID - Names and Identifiers

Name	7-Methoxycarbonyl-1H-indazole-3-carboxylic acid
Synonyms	1H-Indazole-3,7-dicarboxylic acid 7-METHOXYCARBONYL-1H-INDAZOLE-3-CARBOXYLIC ACID 7-Methoxycarbonyl-1H-indazole-3-carboxylic acid 7-(Methoxycarbonyl)-1H-indazole-3-carboxylicacid 7-Methoxycarbonyl-1H-indazole-3- carboxylic acid 1H-Indazole-3,7-dicarboxylic acid 7-methyl ester 1H-Indazole-3,7-dicarboxylic acid, 7-methyl ester 1H-Indazole-3,7-dicarboxylic acid, 7-Methyl ester 7-(Methoxycarbonyl)-1H-indazole-3-carboxylic acid
CAS	898747-36-9
EINECS	200-258-5
InChI	InChI=1S/C10H8N2O4/c1-16-10(15)6-4-2-3-5-7(6)11-12-8(5)9(13)14/h2-4H,1H3,(H,11,12)(H,13,14)

7-METHOXYCARBONYL-1H-INDAZOLE-3-CARBOXYLIC ACID - Physico-chemical Properties

Molecular Formula	C10H8N2O4
Molar Mass	220.18
Storage Condition	2-8°C

7-METHOXYCARBONYL-1H-INDAZOLE-3-CARBOXYLIC ACID - Introduction

Acid is an organic compound with the chemical formula C11H9N2O4. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: acid is a white crystalline solid.
-Melting point: about 160-165°C.
-Solubility: The compound is soluble in some organic solvents (such as dichloromethane, dimethyl sulfoxide, etc.), but has low solubility in water.

Use:
-Drug intermediate: acid can be used as an important intermediate in drug synthesis and has a wide range of application prospects.

Preparation Method:
At present, there are few reports on the preparation method of acid. Can refer to the following method preparation:
1. using pyrrole and N-methyl-N-nitro-formamide reaction, 7-methoxycarbonyl-1H-indazole-3-carboxylic acid methyl ester.
2. The methyl 7-methoxycarbonyl-1H-indazole-3-carboxylate is hydrolyzed with alkali to obtain the target product acid.

Safety Information:
Due to the lack of specific safety assessment results, please take proper laboratory safety measures when handling, avoid inhalation, contact with skin or ingestion. Make sure to operate under proper ventilation conditions and wear appropriate personal protective equipment, such as laboratory gloves, protective glasses and laboratory coats. In case of accidental exposure or discomfort, seek medical help promptly.

Last Update：2024-04-09 19:05:52